Kingfisher Biotech Circular
Context is critical for the pivotal functions of Interleukin-6

Interleukin-6 (IL-6), once known as interferon-beta 2, has long been studied for its role in pro-inflammatory responses, notably the acute phase response and B cell maturation. However, the vastly pleiotropic functions of IL-6 have begun to be appreciated, including an anti-inflammatory role for IL-6 as a myokine in response to physical stress. To achieve such different outcomes a complex interplay is required between various cytokines, receptors and signaling pathways, much of which still requires elaboration. For instance, IL-6 can be recognized by either a surface or soluble IL-6 receptor. Evolutionary conservation of distant piscine orthologs, associations with a wide assortment of autoimmune disorders and cancers, and the availability of monoclonal antibody therapies targeting both IL-6 and IL-6R further emphasize the importance of understanding this multifunctional cytokine. more...

New Proteins

Antibody Cross-reactivity

Many of our antibodies work across species. Check out our antibody cross-reactivity tables to find the antibody that works with your specie. We have two tables - one for our antibodies to cytokines and one for our antibodies to cell surface markers.

5 New Do-It-Yourself ELISAs

Kingfisher Biotech offers over 90 pairs of antibodies and proteins across eleven species that have been shown to work in ELISA. Our newest pairs include, Bovine CCL11, Mouse IL-1 beta, Mouse IL-22, Guinea Pig IL-8, and Canine CCL2.

Kingfisher Biotech, Inc. is committed to accelerating basic veterinary research and human disease research done in animal models by developing and commercializing research reagents specific for a variety of species. We will continue to add species as our customer request specific reagents for their research. Currently, we offer over 1000 reagents and kits for veterinary and animal model research. If there is a product that you are looking for and can't find, please send us an email.

APRIL (TNFSF13)BAFF (TNFSF13B)CCL2 (MCP-1)CCL3 (MIP-1 alpha)CCL3L1CCL4 (MIP-1 beta)CCL5 (RANTES)CCL11 (Eotaxin)CCL20CXCL1 (GRO alpha)CXCL9 (MIG)CXCL10 (IP-10)CXCL11 (I-TAC)CXCL12FGF basicGM-CSFIFN alphaIFN betaIFN gammaIGF-1IGF-2IL-1 alphaIL-1 betaIL-1F5IL-1 receptor antagonistIL-2IL-4IL-5IL-6IL-8 (CXCL8)IL-10IL-12 p40IL-13IL-15IL-16,IL-17AIL-17FIL-18IL-21IL-22IL-23AIL-24M-CSFMIFRANKL (TNFSF11)SCF,TNF alphaTNFSF15 (TL1A)TWEAKVEGF-A

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