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CartMouse Oncostatin M (OSM) Do-It-Yourself ELISA, ≤10 Plates
Mouse OSM ELISA Data
Mouse OSM ELISA Kit Components
| Component | Use | Quantity | Catalog # |
| Anti-Mouse OSM Polyclonal Antibody | Capture Antibody | 100 µg | KP1436M-100 |
| Biotinylated Anti-Mouse OSM Polyclonal Antibody | Detection Antibody | 50 µg | KPB1437M-050 |
| Mouse OSM Recombinant Protein | Standard | 5 µg | RP1222M-005 |
Mouse OSM ELISA Specifications
The Mouse OSM Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Mouse OSM ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA have not been determined. A working knowledge of ELISA is strongly recommended. The quantities of components provided are not matched. Components may also be purchased separately.
For additional tips and techniques to ensure a successful ELISA, check out our ELISA Technical Guide.
Oncostatin M (OSM) Background
OSM (Oncostatin M) is a secreted cytokine involved in homeostasis and most chronic illnesses. OSM, a member of the IL-6 (gp130) family of proteins, inhibits the proliferation of a number of tumor cell lines and plays a significant role in hematopoiesis, mesenchymal stem cell differentiation, liver regeneration, heart remodeling, nociception, inflammation and metabolism. Of all IL-6-type cytokines studied so far, OSM displays the broadest signaling profile. LIF and OSM proteins activate the JAK/STAT pathway, the MAPK protein kinases ERK1 and ERK2, the stress-activated protein kinases p38 and c-Jun N-terminal kinase (JNK), the phosphatidylinositol-3-kinase (PI3K) AKT pathway and protein kinase C delta (PRKCD). In addition, OSM exhibits many other effects by regulating the production of other cytokines including IL-6, G-CSF and GM-CSF in endothelial cells. OSM may be a tumor promoter that will provide a potential target for antiangiogenic therapy.
Alternate Names - OSM, Osm, OncoM, oncostatin M
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Kingfisher Biotech, Inc.
1000 Westgate Drive
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Saint Paul, MN 55114
USA
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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.
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