Egyptian Rousette Bat IL-17A Polyclonal Antibody

Catalog Number:
KP2269BT
Availability:
In stock
Application:
ELISA, ELISpot, Flow Cytometry, Neutralization, Western Blot
Host:
Rabbit
100% Homology:
Rousettus aegyptiacus (Egyptian rousette)
Label:
Unconjugated
  • The Egyptian Rousette Bat IL-17A polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Egyptian Rousette Bat IL-17A ELISA. The Egyptian Rousette Bat IL-17A antibody was produced in rabbits and is antigen-affinity purified. This antibody has been show to cross-react with various IL-17A proteins - Recombinant bovine IL-17A (Strong), Recombinant canine IL-17A (None), Recombinant caprine IL-17A (None), Recombinant chicken IL-17A (None), Recombinant cynomolgus monkey IL-17A (Weak), Recombinant dolphin IL-17A (Strong), Recombinant equine IL-17A (Moderate), Recombinant feline IL-17A (Moderate), Recombinant ferret IL-17A (Weak), Recombinant guinea pig IL-17A (None), Recombinant human IL-17A (Weak), Recombinant mallard IL-17A (None), Recombinant mouse IL-17A (Weak), Recombinant ovine IL-17A (Strong), Recombinant rabbit IL-17A (Moderate), Recombinant rat IL-17A (None), Recombinant swine IL-17A (Moderate), Recombinant zebrafish IL-17af1 (None). For research use only.
Storage Conditions2°C to 8°C
PurificationAntigen-affinity
Country Of OriginUSA
Egyptian rousette bat IL-17A (Interleukin-17A) is a pro-inflammatory cytokine belonging to the IL-17 family that plays a key role in regulating host defense and inflammatory responses in the Egyptian rousette bat (Rousettus aegyptiacus). IL-17A is produced primarily by Th17 cells and other IL-17–producing lymphocytes, including γδ T cells and innate lymphoid cells, in response to infection or immune stimulation. It acts on epithelial, endothelial, and stromal cells to induce expression of pro-inflammatory cytokines, chemokines, and antimicrobial peptides, thereby promoting neutrophil recruitment and enhancing mucosal immunity. In healthy bats, basal IL-17A expression is expected to be low, but levels may increase during bacterial or fungal infection, tissue injury, or experimental immune activation. Given that Egyptian rousette bats are natural reservoir hosts for pathogens such as Marburg virus and other zoonotic viruses, characterization of IL-17A responses in this species is of particular interest for understanding how bats balance effective pathogen control with limited immunopathology. Study of Egyptian rousette bat IL-17A provides valuable insight into Th17-mediated immunity, mucosal defense mechanisms, and the unique immune regulatory strategies that enable bats to tolerate viral infections.

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