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Ovine VEGF-A Polyclonal Antibody - Biotinylated
- Catalog Number:
- PBB0910V
- Availability:
- In stock
- Application:
- ELISA, ELISpot
- Host:
- Goat
- 100% Homology:
- Oryx dammah (scimitar-horned oryx), Ovis aries (sheep), Pantholops hodgsonii (chiru)
- Label:
- Biotin
- The Ovine VEGF-A polyclonal antibody is labeled and has been qualified for use in ELISA. It is the detection antibody in the Kingfisher Biotech Canine VEGF-A ELISA. The Ovine VEGF-A antibody was produced in goats and is antigen-affinity purified. The reactivity by species is: (Bovine VEGF-A - Moderate) (Canine VEGF-A - Weak) (Equine VEGF-A - Weak) (Feline VEGF-A - Weak) (Mouse VEGF-A - Weak) (Ovine VEGF-A - Strong) (Rat VEGF-A - Weak) (Swine VEGF-A - Moderate). For research use only.
| Storage Conditions | 2°C to 8°C |
| Purification | Antigen-affinity |
| Country Of Origin | USA |
- Ovine Vascular Endothelial Growth Factor A (VEGF-A) is a member of the vascular endothelial growth factor (VEGF) family, which includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, and placental growth factor (PlGF)-key regulators of angiogenesis, vascular permeability, and endothelial cell growth. In sheep (Ovis aries), VEGF-A is produced by a variety of cell types including endothelial cells, macrophages, fibroblasts, epithelial cells, smooth muscle cells, and trophoblast cells, particularly in response to hypoxia, inflammation, and tissue injury. VEGF-A exerts its biological effects primarily through binding to VEGF receptor-1 (VEGFR-1/Flt-1) and VEGF receptor-2 (VEGFR-2/KDR) on endothelial cells, activating intracellular signaling pathways such as MAPK/ERK, PI3K/AKT, and PLCγ, which promote endothelial cell proliferation, migration, vascular permeability, and formation of new blood vessels. In ovine physiology, VEGF-A plays important roles in placental vascular development, reproductive function, fetal growth, and tissue repair, supporting the formation of an adequate maternal-fetal blood supply during pregnancy. VEGF-A is also involved in wound healing and vascular remodeling following tissue injury. Because sheep are widely used as large-animal models for cardiovascular physiology, placental biology, and fetal development, ovine VEGF-A is studied in research on angiogenesis, reproductive biology, and vascular regulation, providing insights relevant to both livestock health and translational biomedical research.
50 ug
Price: $400.00
