Slide 1 of 1 
Equine CXCL9 (MIG) Recombinant Protein
- Catalog Number:
- RP0057E
- Availability:
- In stock
- Application:
- Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
- 100% Homology:
- Equus caballus (horse), Equus przewalskii (Przewalski's horse)
- Equine CXCL9 (alias MIG, monokine induced by gamma interferon) (catalog RP0057E) is a yeast-derived chemokine supplied lyophilized without carrier protein in 10% trehalose; it has no affinity tags and is naturally endotoxin-free, and should be reconstituted in sterile PBS that contains at least 0.1% carrier protein. The protein is ~12.0 kDa, 104 amino acids long (full sequence provided), and >98% pure by SDS-PAGE, with 100% amino-acid homology across horse and Przewalski's horse. Store at -20°C (stable up to twelve months from date of receipt; working aliquots with carrier protein stable at least 3 months) and avoid repeated freeze/thaw cycles. Product origin is the USA. Kingfisher Biotech products are supplied for research applications and are not intended for medicinal, diagnostic, or therapeutic use. It is commonly used in immunology and cell-biology research to study chemokine signaling and leukocyte chemoattraction/migration (particularly CXCR3⁺ T cells and NK cells), inflammation and immune-cell trafficking; typical experimental uses include chemotaxis and cell-migration assays, receptor-binding and signaling studies, cell-culture stimulation and dosing, ELISA and neutralization assays, flow-cytometry and Western blot controls, and antibody generation/validation.
| Amino Acid Sequence | APVMRKGRCS CIKTSQGTIR PKLLKDLKQF APSPSCETTE IIATMKNGDQ TCLNPDSAEV KELIKEWEKQ VSQKKKQKKG KKHQKTKKFP KVKKWQRPRQ KKAT (104) |
| Endotoxin | Naturally endotoxin-free |
| Storage Conditions | -20°C |
| Molecular Weight | 12.0kDa |
| Purity | >98% as visualized by SDS-PAGE analysis. |
| Country Of Origin | USA |
- Equine CXCL9 (C-X-C motif chemokine ligand 9), also known as MIG (monokine induced by interferon-γ), is a proinflammatory chemokine belonging to the CXC chemokine family, which also includes CXCL10 (IP-10) and CXCL11 (I-TAC) that regulate T-cell recruitment during interferon-driven immune responses. In horses (Equus caballus), CXCL9 is produced by macrophages, dendritic cells, endothelial cells, and epithelial cells in response to interferon-γ (IFN-γ) and inflammatory stimuli during infection or immune activation. CXCL9 signals primarily through the chemokine receptor CXCR3, which is expressed on activated T lymphocytes, natural killer (NK) cells, and other immune cells, promoting chemotaxis and accumulation of these cells at sites of infection or inflammation. In equine health, CXCL9 contributes to cell-mediated immune responses against intracellular pathogens, particularly in tissues such as the respiratory tract and lymphoid organs. CXCL9-mediated recruitment of Th1-type T cells is important in immune responses to viral and bacterial infections, including diseases such as equine herpesvirus infections, where interferon-driven chemokine signaling helps coordinate antiviral immunity and inflammatory responses. Consequently, equine CXCL9 is studied in veterinary immunology and infectious disease research to better understand T-cell trafficking, interferon-mediated immunity, and host-pathogen interactions in horses.
Please choose a size to see price
