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Ovine CXCL10 (IP-10) (Yeast-derived Recombinant Protein) - 500 ug (5 x 100 ug vials)

RP0490V-500
$3300.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3.

Alternate Names - CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10

Homology Across Species
Ovis aries (sheep) CXCL10 – 100%
Capra hircus (goat) CXCL10 – 99%
​More - https://blast.ncbi.nlm.nih.gov/

Ovine CXCL10 (IP-10) (Yeast-derived Recombinant Protein) - 500 ug (5 x 100 ug vials)
Catalog No.:
RP0490V-500
Quantity:
500 ug (5 x 100 ug vials)
Source:
Ovine CXCL10/IP-10 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
Ovine CXCL10/IP-10 has a predicted molecular weight of 9.4 kDa.
Protein Sequence:
IPLSRNTRCT CIEISNGSVN PRSLEKLELI PASQSCPRVE IIATMKRNGE KRCLNPESKT IKNLLKAINK QRTKRSPRTQ KEA (83)
Alias:
IP-10
Country of Origin:
USA
Applications:
The Ovine CXCL10 (IP-10) endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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