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Rat RANKL (TNFSF11) (Yeast-derived Recombinant Protein) - 25 micrograms

RP0734R-025
$300.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

Tumor necrosis factor ligand superfamily member 11 (TNFSF11) also known as Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF) is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18). RANKL regulates bone remodelling and the development of the thymus, lymph nodes and mammary glands. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and psoriatic arthritis.

Alternate Names - TNFSF11, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf, TNLG6B, tumor necrosis factor superfamily member 11, TNF superfamily member 11

Rat RANKL (TNFSF11) (Yeast-derived Recombinant Protein) - 25 micrograms
Catalog No.:
RP0734R-025
Quantity:
25 ug
Source:
Mouse RANKL was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
Rat RANKL has a predicted molecular weight of 19.8 kDa.
Protein Sequence:
FSGVPAMMEG SWLDVARRGK PEAQPFAHLT INAANIPSGS HKVSLSSWYH DRGWAKISNM TLSNGKLRVN QDGFYYLYAN ICFRHHETSG SVPADYLQLM VYVVKTSIKI PSSHNLMKGG STKNWSGNSE FHFYSINVGG FFKLRAGEEI SVQVSNPSLL DPDQDATYFG AFKVQDID (178)
Alias:
RANKL
Country of Origin:
USA
Applications:
The Rat RANKL endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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