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Guinea Pig Leukemia Inhibitory Factor (LIF) (Yeast-derived Recombinant Protein) - 100 micrograms

RP1069GP-100
$900.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

Leukemia inhibitory factor, or LIF, is a member of the IL-6 family. LIF affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. Leukemia inhibitory factor derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to LIF include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. LIF is typically added to stem cell culture medium to reduce spontaneous differentiation.

Alternate Names - LIF, CDF, DIA, HILDA, MLPLI, leukemia inhibitory factor, interleukin 6 family cytokine, LIF interleukin 6 family cytokine

Homology Across Species
Cavia porcellus (domestic guinea pig) LIF – 100%
Chinchilla lanigera (long-tailed chinchilla) LIF – 96%
More - https://blast.ncbi.nlm.nih.gov/

Guinea Pig Leukemia Inhibitory Factor (LIF) (Yeast-derived Recombinant Protein) - 100 micrograms
Catalog No.:
RP1069GP-100
Quantity:
100 ug
Source:
Guinea Pig LIF was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
Guinea Pig LIF has a predicted molecular weight of 19.8 kDa.
Protein Sequence:
SPLPITPVNA TCATRHPCPS NVMSQIRNQL AQLNSSANAL FILYYTAQGE PFPNNLDKLC APNVTDFPPF HANGTEKVKL VELYRIIAYL GAALGNITHD QKLLNPNALS LHSKLSVTAD VMRGLLSNVH CRLCNKYHVA HVDVTYGPDT SDKDVFQKKK LGCQLLGKYK QVIGVVTQAF (180)
Alias:
LIF
Country of Origin:
USA
Applications:
The Guinea Pig LIF endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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