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Dolphin IL-13 (Yeast-derived Recombinant Protein) - 5 microgrmas

RP1094P-005
$150.00
In Stock
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Bulk quantities of Dolphin IL-13 protein are available.
Please contact us for pricing.

Dolphin IL-13 Specifications

Molecular Weight (calculated) - 12.4kDa

Amino Acid Sequence - GPVPPSTALK ELIEELVNIT QNQKAPLCNG SMVWSVNLTA NMYCSALEAL INVSNCSAIQ RTQRMLSALC LHKPSAGQVS SEHIRDTKIE VAHFLKDLLK HSRIIFHYGK FS (112)

Gene ID - 101338603

Homology Across Species
Tursiops truncatus (common bottlenose dolphin) IL-13 – 100%
Orcinus orca (killer whale) IL-13 – 100%
Globicephala melas (long-finned pilot whale) IL-13 – 100%
Phocoena sinus (vaquita) IL-13 – 100%
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) IL-13 – 100%
Lipotes vexillifer (Yangtze River dolphin) IL-13 – 99%
Lagenorhynchus obliquidens (Pacific white-sided dolphin) IL-13 – 98%
Delphinapterus leucas (beluga whale) IL-13 – 98%
Physeter catodon (sperm whale) IL-13 – 96%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

IL-13 Background

Interleukin 13 (IL-13) is secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. Thus, although IL-13 can induce immunoglobulin E (IgE) secretion from activated human B cells, deletion of IL-13 from mice does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. In comparison, deletion of IL-4 abrogates these responses. Thus, rather than a lymphoid cytokine, IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Alternate Names - IL13, IL-13, P600, interleukin 13

Dolphin IL-13 (Yeast-derived Recombinant Protein) - 5 microgrmas
Catalog No.:
RP1094P-005
Quantity:
5 ug
Source:
The Dolphin IL-13 recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Dolphin IL-13 recombinant protein has a predicted molecular weight of 12.4 kDa.
Protein Sequence:
GPVPPSTALK ELIEELVNIT QNQKAPLCNG SMVWSVNLTA NMYCSALEAL INVSNCSAIQ RTQRMLSALC LHKPSAGQVS SEHIRDTKIE VAHFLKDLLK HSRIIFHYGK FS (112)
Country of Origin:
USA
Applications:
The Dolphin IL-13 endotoxin-free recombinant protein can be used in cell culture, as an IL-13 ELISA Standard, and as a Western Blot Control.
None at this time

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