Mouse CCL11 (C-C motif chemokine ligand 11), also known as eotaxin-1, is a member of the CC chemokine family that plays a key role in regulating eosinophil recruitment and type 2–associated immune responses in mice (Mus musculus). CCL11 is produced primarily by epithelial cells, fibroblasts, endothelial cells, smooth muscle cells, and activated immune cells in response to Th2-associated cytokines such as IL-4 and IL-13, as well as inflammatory stimuli. It functions predominantly through the CCR3 receptor to promote chemotaxis and activation of eosinophils, and also influences basophils and certain Th2 lymphocytes. In healthy mice, basal CCL11 expression is typically low but increases significantly during allergic airway inflammation, helminth infection, experimental asthma models, and other Th2-skewed immune responses. Mouse CCL11 is widely studied in models of asthma, allergic inflammation, eosinophilic gastrointestinal disease, and parasitic infection, where eosinophil infiltration and type 2 cytokine responses are central features of pathology. Characterization of CCL11 in mice provides valuable insight into chemokine-mediated leukocyte trafficking, eosinophil biology, and mechanisms underlying allergic and type 2–driven inflammatory diseases in translational research.