Rabbit CCL20 (C-C motif chemokine ligand 20, also known as MIP-3α, macrophage inflammatory protein-3 alpha, or LARC – liver and activation-regulated chemokine) is a pro-inflammatory chemokine that plays an important role in mucosal immunity and leukocyte recruitment in rabbits (Oryctolagus cuniculus). CCL20 signals specifically through the CCR6 receptor, promoting chemotaxis of immune cells including immature dendritic cells, memory T cells, Th17 cells, regulatory T cells, and certain B cell populations to sites of epithelial infection or inflammation. In rabbits, CCL20 is produced by epithelial cells, fibroblasts, macrophages, and other immune cells in response to microbial products and inflammatory cytokines such as IL-1β, TNF-α, and IL-17. Expression is particularly prominent at mucosal surfaces, including the intestinal tract, respiratory epithelium, and skin, where it contributes to recruitment of antigen-presenting cells and coordination of adaptive immune responses. In rabbit health and research, CCL20 is relevant in studies of bacterial enteric infections, respiratory inflammation, and skin immune responses, as well as in experimental models of mucosal immunity and inflammatory disease. Because rabbits are widely used as translational models for immunology, infectious disease, and mucosal vaccine research, characterization of rabbit CCL20 supports investigations into chemokine-mediated immune cell trafficking, epithelial immune signaling, and inflammatory mechanisms relevant to both veterinary and human health.