Feline SCF (165aa) (Yeast-derived Recombinant Protein) - 5 micrograms

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Bulk quantities of proteins are available. Please contact us for bulk pricing.

SCF, often known as Kit Ligand, KITL or KITLG, is involved in pathways that control the regulation of cell survival, migration and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, and melanogenesis. SCF binding to the receptor-type protein-tyrosine kinase KIT, induces a cell signaling pathway that activates several other cell signaling pathways, including PIK3R1/AKT1, GRB2, RAS, RAF1, MAPK1/ERK2, MAPK3/ERK1, and STAT signaling events. The effects of SCF on these secondary pathways further allow it to play a role in many or the major cellular processes. The SCF, of most vertebrates, has a soluble form as well as the membrane bound type I receptor form. Mutations in the SCF pathway may result in a broad range of abnormalities including anemia, and sterility. SCF and KIT interaction has been shown to promote the growth of cancer cells and organoids in culture, and xenograft tumors in mice. SCF is being utilized in many animal model systems, from metastasis research in breast tumor-bearing arthritic mice to the genetic linkage to de-pigmentation in pigs. Interestingly, a second SCF pathway was retained in zebrafish, after a whole genome duplication, and is now undergoing divergent evolution.

Alternate Names - KITLG, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, DCUA, KIT ligand, DFNA69, SLF

SCF Homology Across Species
Felis catus (domestic cat) SCF – 100%
Acinonyx jubatus (cheetah) SCF – 100%
Panthera pardus (leopard) SCF – 100%
Panthera tigris altaica (Amur tiger) SCF – 100%
Ceratotherium simum simum (southern white rhinoceros) SCF – 95%
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Catalog No.:
5 ug
The Feline SCF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
The Feline SCF recombinant protein has a predicted molecular weight of 18.4 kDa.
Protein Sequence:
Kit Ligand, Stem Cell Factor
Country of Origin:
The Feline SCF endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
None at this time

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Kingfisher Biotech, Inc.
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