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Human EGF (Yeast-derived Recombinant Protein) - 5 micrograms

RP1424H-005
$150.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

EGF (Epidermal Growth Factor) is best known for having the ability to stimulate cell growth and proliferation. There are many EGF responses and they are regulated by seven ligands: EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF-like growth factor (HBEGF), betacellulin (BTC), amphiregulin (AREG), epiregulin (EREG), and epigen (EPGN) and four ErbB (HER) family receptor tyrosine kinases: EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. EGF family members are important for development and promoting mitogenesis and differentiation of mesenchymal and epithelial cells. EGF acts as a mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. EGF plays a significant role in epithelial development, angiogenesis, regulation of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture. EGF dysregulation is also associated with the growth and progression of many cancers.

Low concentrations of EGF distinguish high-producing and repeat breeder cows from normal cows. The dairy cows having a normal EGF expression profile show a higher pregnancy rate than cows with aberrant EGF expression profiles. Evidence links EGF to embryogenesis and/or implantation in mammalian species by influencing growth-promoting activities on the conceptus and endometrium. EGF regulation is especially crucial in breeding pigs because they have a non-invasive placentation and a prolonged implantation period.

Alternate Names - EGF, HOMG4, URG, epidermal growth factor, Epidermal growth factor​

Amino Acid Homology Across Species
Homo sapiens (human) EGF – 100%
Pan paniscus (pygmy chimpanzee) EGF – 100%
Pan troglodytes (chimpanzee) EGF – 100%
Gorilla gorilla gorilla (western lowland gorilla) EGF – 100%

Catalog No.:
RP1424H-005
Quantity:
5 ug
Source:
The Human EGF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Human EGF recombinant protein has a predicted molecular weight of 6.2 kDa.
Protein Sequence:
NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR (53)
Alias:
Epidermal Growth Factor
Country of Origin:
USA
Applications:
The Human EGF endotoxin-free recombinant protein can be used in cell culture, as an EGF ELISA Standard, and as a Western Blot Control.
None at this time

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Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA

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Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.

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