Slide 1 of 1 
Bovine Placental Growth Factor (PlGF) Recombinant Protein
- Catalog Number:
- RP1446B
- Availability:
- In stock
- Application:
- Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
- 100% Homology:
- Bison bison bison (American buffalo), Bos indicus (zebu), Bos mutus (wild yak), Bos taurus (cattle)
- Bovine PlGF (Placental Growth Factor) (catalog RP1446B) is a yeast-derived growth factor supplied lyophilized without carrier protein in 10% trehalose; it has no affinity tags and is naturally endotoxin-free, and should be reconstituted in sterile PBS that contains at least 0.1% carrier protein. The protein is ~15.1 kDa, 131 amino acids long (full sequence provided), and >98% pure by SDS-PAGE, with 100% amino-acid homology to cattle, American buffalo, zebu, and wild yak. Store at -20°C (stable up to twelve months from date of receipt; working aliquots with carrier protein stable ~3 months) and avoid repeated freeze/thaw cycles. Product origin is the USA. It is commonly used to study PlGF signaling and vascular biology (including regulation of angiogenesis, vascular development, and endothelial cell function); typical experimental uses include cell-culture stimulation and angiogenesis assays, signaling studies, ELISA and neutralization assays, flow-cytometry and Western blot controls, and antibody generation/validation. Kingfisher Biotech products are supplied for research applications and are not intended for medicinal, diagnostic, or therapeutic use.
| Amino Acid Sequence | LPAVPTTQWA LSPGNISSEV EVVPFQQVWS RSYCRPVERL VDIVSEYPSE MEHLFSPSCV SLMRCTGCCS DESMHCVPLE TANVTMQLMK YRSLDQPFFV EMSFSQHVRC ECKPLWEKMK QTRCGDTISQ R (131) |
| Endotoxin | Naturally endotoxin-free |
| Storage Conditions | -20°C |
| Molecular Weight | 15.1 kDa |
| Purity | >98% as visualized by SDS-PAGE analysis. |
| Country Of Origin | USA |
- Bovine Placental Growth Factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of angiogenic growth factors, which also includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, and VEGF-E. In cattle (Bos taurus), PlGF functions primarily as a regulator of angiogenesis, vascular remodeling, and placental development. PlGF binds mainly to the VEGF receptor-1 (VEGFR-1/Flt-1) on endothelial and other target cells, activating signaling pathways that promote endothelial cell proliferation, migration, and new blood vessel formation. In bovine physiology, PlGF is expressed in the placenta, uterine tissues, and other vascularized organs, where it contributes to placental vascularization, maternal-fetal nutrient exchange, and successful pregnancy establishment and maintenance. PlGF signaling also participates in tissue repair and inflammatory responses, influencing recruitment of macrophages and modulation of vascular growth during tissue remodeling. Because proper placental vascular development is critical for fetal growth, reproductive efficiency, and pregnancy success in cattle, bovine PlGF is studied in research on placental biology, reproductive physiology, angiogenesis, and pregnancy-associated disorders, contributing to improved understanding of reproductive health and productivity in livestock.
Please choose a size to see price
RELATED MEDIA
