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Swine IL-25 (IL-17E) (Yeast-derived Recombinant Protein) - 25 micrograms

RP1678S-025
$300.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

IL-25, also kown as IL-17E, is a member of the IL-17 family. Other members include IL-17A, IL-17B, IL-17C, IL-17D, IL-17F. All members have homologous amino acid sequence segments and spatially conserved cysteines. IL-25 is produced by many cell types. These cells include T cells, dendritic cells, macrophages, mast cells, basophils, eosinophils, epithelial cells and Paneth cells. This cytokine can induce NF-κB activation, and stimulate the production of IL-8 (aka CXCL8), which is the major chemotactic substance of neutrophils. IL-25 also supports the Th2 immune response. It has been shown to induce the production of IL-4, IL-5 and IL-13. Evidence is the expression of IL-17RB on Th2 cells, not on Th1 and Th17. In addition, IL-25 is responsible for the decrease in IFN gamma.

Alternate Names - IL25, IL17E, IL-25, interleukin 25

Amino Acid Homology Across Species
Sus scrofa (pig) IL-25 – 100%
More… https://blast.ncbi.nlm.nih.gov

Catalog No.:
RP1678S-025
Quantity:
25 ug
Source:
The Swine IL-25 (IL-17E) recombiniant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Swine IL-25 (IL-17E) recombinant protein has a predicted molecular weight of 17.1 kDa.
Protein Sequence:

WSQKGCPHWP NCCPSKGQNP IEEWLKQNAV LMPPLEMASP TPHPESCKAS EDGPLNSRSI APWRYELDRD LNRLPQDLYH ARCLCPHCVS LRTGSHMDPL GNSELLYHNQ TVFYRRPCPG QQGAHDSYCL EPRLYQVSLA CVCVRPRVMA (150)

Alias:
IL-17E
Country of Origin:
USA
Applications:
The Swine IL-25 (IL-17E) endotoxin-free recombinant protein can be used in cell culture, as an IL-25 ELISA Standard, and as a Western Blot Control.
None at this time

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