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Swine IL-16 Recombinant Protein
- Catalog Number:
- RP1700S
- Availability:
- In stock
- Application:
- Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
- 100% Homology:
- Sus scrofa (pig)
- Swine IL-16 (Interleukin-16) (catalog RP1700S) is a yeast-derived cytokine supplied lyophilized without carrier protein in 10% trehalose; it has no affinity tags and is naturally endotoxin-free, and should be reconstituted in sterile PBS that contains at least 0.1% carrier protein. The protein is ~13.4 kDa, 130 amino acids long (full sequence provided), and >98% pure by SDS-PAGE, with 100% amino-acid homology to pig. Store at -20°C (stable up to twelve months from date of receipt; working aliquots with carrier protein stable ~3 months) and avoid repeated freeze/thaw cycles. Product origin is the USA. It is commonly used to study IL-16 signaling and immune responses (including roles in T-cell chemoattraction, immune regulation, and inflammatory pathways); typical experimental uses include cell-culture stimulation and chemotaxis assays, cytokine signaling studies, ELISA and neutralization assays, flow-cytometry and Western blot controls, and antibody generation/validation. Kingfisher Biotech products are supplied for research applications and are not intended for medicinal, diagnostic, or therapeutic use.
| Amino Acid Sequence | ASPDLNSSTD SAASVSVASD ISIDSTEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFRGAAS EQNETIQPGD EILHLAGTAV QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKGTTGAGDP (130) |
| Endotoxin | Naturally endotoxin-free |
| Storage Conditions | -20°C |
| Molecular Weight | 13.4 kDa |
| Purity | >98% as visualized by SDS-PAGE analysis. |
| Country Of Origin | USA |
- Swine Interleukin-16 (IL-16) is a proinflammatory cytokine that plays an important role in regulating immune cell recruitment and activation in pigs (Sus scrofa). IL-16 is produced by several cell types, including CD8⁺ T cells, mast cells, eosinophils, and epithelial cells, in response to immune stimulation or inflammatory signals. Swine IL-16 functions primarily as a chemoattractant for CD4⁺ immune cells by binding to the CD4 receptor, promoting migration and activation of T helper cells, monocytes, and dendritic cells to sites of infection or inflammation. Through these actions, IL-16 contributes to coordination of immune responses and modulation of inflammatory signaling pathways. In pigs, IL-16 participates in immune responses against bacterial, viral, and parasitic pathogens and may influence inflammatory processes in tissues such as the respiratory and gastrointestinal tracts. Swine IL-16 is studied in veterinary immunology and infectious disease research, including investigations of immune responses to important swine pathogens such as porcine reproductive and respiratory syndrome virus (PRRSV), African swine fever virus (ASFV), and Salmonella spp., where IL-16-mediated immune cell recruitment contributes to regulation of inflammatory and host defense mechanisms.
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