Cart

Duck CCL19 (MIP-3 beta)(Yeast-derived Recombinant Protein) - 5 micrograms

RP1748MD-005
$150.00
In Stock
Add to Cart

Bulk quantities of proteins are available. Please contact us for bulk pricing.

CCL19 (also known as MIP-3 beta) and CCL21, the ligands for CCR7, are involved in controlling a diverse array of migratory events in adaptive immune functions such as the homing of Dendritic and T-Cells to areas of lymphoid tissues where T-cell priming occurs. These predominant chemokines play an important role in many aspects of the immune model systems, as well as general animal health. CCL19 or CCL21 induced expression in tumor tissue, from various cancer models, results in an inhibition of tumor growth and may even lead to a complete rejection of several tumors due to this increased infiltration by dendritic and/or T-cells. Both CCL19 and CCL21 are predominantly expressed in the thymic medulla and also contribute to a multitude of adaptive immune functions including thymocyte development, secondary lymphoid organogenesis, high affinity antibody responses, regulatory and memory T-cell function, and lymphocyte migration from tissues. CCL19, unlike CCL21, induces beta arrestin recruitment, which leads to receptor desensitization and internalization. Effective priming of T-cell responses depends on the interactions between naive T-cells and antigen-presenting cells (APCs). Several animal model systems have been used to characterize the role of the CCL19, CCL21, CCR7 ligand system in T-cell responses during infection.

Alternate Names - CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19, C-C motif chemokine ligand 19

Homology Across Species
Anas platyrhynchos (mallard) CCL19 – 100%
Aythya fuligula (tufted duck) CCL19 – 97%
Cygnus atratus (black swan) CCL19 – 96%
Oxyura jamaicensis (ruddy duck) CCL19 – 96%
​More - https://blast.ncbi.nlm.nih.gov/

Catalog No.:
RP1748MD-005
Quantity:
5 ug
Source:
The Duck CCL19 (MIP-3 beta) recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Duck CCL19 (MIP-3 beta) endotoxin-free recombinant protein has a predicted molecular weight of 8.6 kDa.
Protein Sequence:

GNNVLDCCLR TSENPIPRRI VQRYQIQLVQ DGCEIPANVF ITVRGKRLCA PLEAPWAVRL REKLDSGSAR KVPNKGN (77)

Alias:
MIP-3 beta
Country of Origin:
USA
Applications:
The Duck CCL19 endotoxin-free recombinant protein can be used in cell culture, as an CCL19 ELISA Standard, and as a Western Blot Control.
None at this time

Ordering Information & Terms and Conditions

Placing Orders
We require a phone number and e-mail address for both the end user of the ordered product and your institution's Accounts Payable representative. This information is only used to help with technical and billing issues.

Via Phone
Please call us at 651-646-0089 between the hours of 8:30 a.m. and 5:30 p.m. CST Mon - Fri.

Via Fax
Orders can be faxed to us 24 hours a day at 651-646-0095.

Via E-mail
Please e-mail orders to orders@KingfisherBiotech.com.

Via Mail
Please mail your order to:
Sales Order Entry
Kingfisher Biotech, Inc.
1000 Westgate Drive
Suite 123
Saint Paul, MN 55114
USA

Product Warranty
Kingfisher Biotech brand products are warranted by Kingfisher Biotech, Inc. to meet stated product specifications and to conform to label descriptions when used, handled and stored according to instructions. Unless otherwise stated, this warranty is limited to one year from date of sale. Kingfisher Biotech’s sole liability for the product is limited to replacement of the product or refund of the purchase price. Kingfisher Biotech brand products are supplied for research applications. They are not intended for medicinal, diagnostic or therapeutic use. The products may not be resold, modified for resale or used to manufacture commercial products without prior written approval from Kingfisher Biotech.

Payment Terms
All prices are subject to change without notice. Payment terms are net thirty (30) days from receipt of invoice. A 1.5% service charge per month is added for accounts past due over 30 days. Prices quoted are U.S. Dollars. The purchaser assumes responsibility for any applicable tax. You will only be charged for products shipped. Products placed on back order will be charged when shipped. If you place an order and fail to fulfill the terms of payment, Kingfisher Biotech, Inc. may without prejudice to any other lawful remedy defer further shipments and/or cancel any order. You shall be liable to Kingfisher Biotech, Inc. for all costs and fees, including attorneys' fees, which Kingfisher Biotech, Inc. may reasonably incur in any actions to collect on your overdue account. Kingfisher Biotech, Inc. does not agree to, and is not bound by, any other terms or conditions such as terms in a purchase order that have not been expressly agreed to in writing signed by a duly authorized officer of Kingfisher Biotech, Inc.

Shipping
Shipping and handling costs are prepaid and added to the invoice. Shipping and handling costs will be charged only on the first shipment in situations where an order contains back ordered products. Kingfisher Biotech, Inc. reserves the right to select the packaging and shipping method for your order, which will ensure the stability of the product and also efficient tracing. Domestic orders will normally be shipped by overnight. Damage during shipment is covered by the warranty provided in these terms and conditions. For international orders, title to the goods passes in the United States when the goods are placed with the shipper. For all orders, the risk of loss of the goods passes when the goods are placed with the shipper.

Returns
Please call customer service before returning any products for refund, credit or replacement. NO returns will be accepted without prior written authorization. Returns are subject to a restocking fee of 20%.