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Swine Prolactin Recombinant Protein
- Catalog Number:
- RP1781S
- Availability:
- In stock
- Application:
- Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control
- 100% Homology:
- Sus scrofa (pig)
- Swine Prolactin (PRL) (catalog RP1781S) is a yeast-derived hormone supplied lyophilized without carrier protein in 10% trehalose; it has no affinity tags and is naturally endotoxin-free, and should be reconstituted in sterile PBS that contains at least 0.1% carrier protein. The protein is ~23.0 kDa, 199 amino acids long (full sequence provided), and >98% pure by SDS-PAGE, with 100% amino-acid homology to pig. Store at -20°C (stable up to twelve months from date of receipt; working aliquots with carrier protein stable ~3 months) and avoid repeated freeze/thaw cycles. Product origin is the USA. It is commonly used to study prolactin signaling and endocrine/immune functions (including regulation of lactation, reproductive biology, and immune modulation); typical experimental uses include cell-culture stimulation and functional assays, hormone and signaling studies, ELISA and neutralization assays, flow-cytometry and Western blot controls, and antibody generation/validation. Kingfisher Biotech products are supplied for research applications and are not intended for medicinal, diagnostic, or therapeutic use.
| Amino Acid Sequence | LPICPSGAVN CQVSLRDLFD RAVILSHYIH NLSSEMFNEF DKRYAQGRGF ITKAINSCHT SSLSTPEDKE QAQQIHHEVL LNLILRVLRS WNDPLYHLVT EVRGMQEAPD AILSRAIEIE EQNKRLLEGM EKIVGQVHPG IKENEVYSVW SGLPSLQMAD EDTRLFAFYN LLHCLRRDSH KIDNYLKLLK CRIIYDSNC (199) |
| Endotoxin | Naturally endotoxin-free |
| Storage Conditions | -20°C |
| Molecular Weight | 23.0 kDa |
| Purity | >98% as visualized by SDS-PAGE analysis. |
| Country Of Origin | USA |
- Swine Prolactin (PRL) is a peptide hormone belonging to the prolactin/growth hormone family, which also includes growth hormone (GH) and placental lactogen-related hormones that regulate growth, metabolism, and reproductive physiology. In pigs (Sus scrofa domesticus), prolactin is produced primarily by lactotroph cells in the anterior pituitary gland and signals through the prolactin receptor (PRLR), activating intracellular pathways such as JAK2/STAT5, MAPK, and PI3K, which regulate gene expression and physiological responses. Swine prolactin plays a critical role in mammary gland development and lactation, supporting milk production necessary for neonatal piglet growth and survival. It also contributes to reproductive function, maternal behavior, and metabolic regulation, influencing processes such as corpus luteum maintenance and seasonal or endocrine regulation of reproduction. In pigs, prolactin can also affect immune responses and mammary gland physiology during the peripartum period. Because pigs are widely used as large-animal models for human physiology, endocrinology, and lactation biology, swine prolactin is studied in research on reproductive endocrinology, mammary gland development, and metabolic regulation, providing insights relevant to both livestock productivity and comparative biomedical research.
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