Canine, Equine, Human, Monkey, Ferret, Dolphin, Bat CXCL14 (Yeast-derived Recombinant Protein) - 25 micrograms

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Chemokine (C-X-C motif) ligand 14 (CXCL14), also known as BRAK (breast and kidney-expressed chemokine) belongs to the CXC chemokine family. CXCL14 is constitutively expressed at high levels in many normal tissues, where its cellular source is thought to be fibroblasts. However, it is reduced or absent from most cancer cells. This chemokine is chemotactic for monocytes and can activate these cells in the presence of an inflammatory mediator called prostaglandin-E2 (PGE2). It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis.

Alternate Names - CXCL14, SCYB14, BRAK, NJAC, bolekine, Kec, MIP-2g, BMAC, KS1

Homology Across Species
Canis lupus familiaris (dog) CXCL14 – 100%
Equus caballus (horse) CXCL14 – 100%
Homo sapiens (human) CXCL14 – 100%
Macaca fascicularis (cynomolgus monkey) CXCL14 – 100%
Mustela putorius furo (domestic ferret) CXCL14 – 100%
Tursiops truncatus (common bottlenose dolphin) CXCL14 – 100%
Artibeus jamaicensis (Jamaican fruit-eating bat) CXCL14 – 100%
Acinonyx jubatus (cheetah) CXCL14 – 100%
Ailuropoda melanoleuca (giant panda) CXCL14 – 100%
Aotus nancymaae (Ma's night monkey) CXCL14 – 100%
Balaenoptera acutorostrata scammony (minke whale) CXCL14 – 100%
Balaenoptera musculus (Blue whale) CXCL14 – 100%
Callithrix jacchus (white-tufted-ear marmoset) CXCL14 – 100%
Callorhinus ursinus (northern fur seal) CXCL14 – 100%
Canis lupus dingo (dingo) CXCL14 – 100%
Castor canadensis (American beaver) CXCL14 – 100%
Cebus imitator (Panamanian white-faced capuchin) CXCL14 – 100%
Ceratotherium simum simum (southern white rhinoceros) CXCL14 – 100%
Cercocebus atys (sooty mangabey) CXCL14 – 100%
Chlorocebus sabaeus (green monkey) CXCL14 – 100%
Chrysochloris asiatica (Cape golden mole) CXCL14 – 100%
Condylura cristata (star-nosed mole) CXCL14 – 100%
Delphinapterus leucas (beluga whale) CXCL14 – 100%
Desmodus rotundus (common vampire bat) CXCL14 – 100%
Elephantulus edwardii (Cape elephant shrew) CXCL14 – 100%
Eptesicus fuscus (big brown bat) CXCL14 – 100%
Equus asinus (ass) CXCL14 – 100%
Equus przewalskii (Przewalski's horse) CXCL14 – 100%
Erinaceus europaeus (western European hedgehog) CXCL14 – 100%
Eschrichtius robustus (grey whale) CXCL14 – 100%
Eumetopias jubatus (Steller sea lion) CXCL14 – 100%
Globicephala melas (long-finned pilot whale) CXCL14 – 100%
Gorilla gorilla gorilla (western lowland gorilla) CXCL14 – 100%
Halichoerus grypus (gray seal) CXCL14 – 100%
Hipposideros armiger (great roundleaf bat) CXCL14 – 100%
Hylobates moloch (silvery gibbon) CXCL14 – 100%
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) CXCL14 – 100%
Lagenorhynchus obliquidens (Pacific white-sided dolphin) CXCL14 – 100%
Leptonychotes weddellii (Weddell seal) CXCL14 – 100%
Lipotes vexillifer (Yangtze River dolphin) CXCL14 – 100%
Lontra canadensis (Northern American river otter) CXCL14 – 100%
Loxodonta africana (African savanna elephant) CXCL14 – 100%
Lynx canadensis (Canada lynx) CXCL14 – 100%
Lynx pardinus (Spanish lynx) CXCL14 – 100%
Macaca mulatta (Rhesus monkey) CXCL14 – 100%
Macaca nemestrina (pig-tailed macaque) CXCL14 – 100%
Mandrillus leucophaeus (drill) CXCL14 – 100%
Manis javanica (Malayan pangolin) CXCL14 – 100%
Marmota flaviventris (yellow-bellied marmot) CXCL14 – 100%
Marmota marmota marmota (Alpine marmot) CXCL14 – 100%
Mirounga leonina (Southern elephant seal) CXCL14 – 100%
Molossus molossus (Pallas's mastiff bat) CXCL14 – 100%
Monodelphis domestica (gray short-tailed opossum) CXCL14 – 100%
Monodon monoceros (narwhal) CXCL14 – 100%
Mustela erminea (ermine) CXCL14 – 100%
Myotis brandtii (Brandt's bat) CXCL14 – 100%
Myotis davidii (vesper bat) CXCL14 – 100%
Myotis lucifugus (little brown bat) CXCL14 – 100%
Myotis myotis (greater mouse-eared bat) CXCL14 – 100%
Neomonachus schauinslandi (Hawaiian monk seal) CXCL14 – 100%
Nomascus leucogenys (northern white-cheeked gibbon) CXCL14 – 100%
Ochotona princeps (American pika) CXCL14 – 100%
Odobenus rosmarus divergens (Pacific walrus) CXCL14 – 100%
Orcinus orca (killer whale) CXCL14 – 100%
Orycteropus afer afer (aardvark) CXCL14 – 100%
Otolemur garnettii (small-eared galago) CXCL14 – 100%
Pan paniscus (pygmy chimpanzee) CXCL14 – 100%
Pan troglodytes (chimpanzee) CXCL14 – 100%
Panthera pardus (leopard) CXCL14 – 100%
Panthera tigris altaica (Amur tiger) CXCL14 – 100%
Papio anubis (olive baboon) CXCL14 – 100%
Phoca vitulina (harbor seal) CXCL14 – 100%
Phocoena sinus (vaquita) CXCL14 – 100%
Phyllostomus discolor (pale spear-nosed bat) CXCL14 – 100%
Physeter catodon (sperm whale) CXCL14 – 100%
Piliocolobus tephrosceles (Ugandan red Colobus) CXCL14 – 100%
Pipistrellus kuhlii (Kuhl's pipistrelle) CXCL14 – 100%
Pongo abelii (Sumatran orangutan) CXCL14 – 100%
Pteropus alecto (black flying fox) CXCL14 – 100%
Pteropus vampyrus (large flying fox) CXCL14 – 100%
Rhinopithecus roxellana (golden snub-nosed monkey) CXCL14 – 100%
Rhinolophus ferrumequinum (greater horseshoe bat) CXCL14 – 100%
Rousettus aegyptiacus (Egyptian rousette) CXCL14 – 100%
Saimiri boliviensis boliviensis (Bolivian squirrel monkey) CXCL14 – 100%
Sapajus apella (Tufted capuchin) CXCL14 – 100%
Sorex araneus (European shrew) CXCL14 – 100%
Suricata suricatta (meerkat) CXCL14 – 100%
Theropithecus gelada (gelada) CXCL14 – 100%
Trachypithecus francoisi (Francois's langur) CXCL14 – 100%
Tupaia chinensis (Chinese tree shrew) CXCL14 – 100%
Urocitellus parryii (Arctic ground squirrel) CXCL14 – 100%
Ursus arctos horribilis (grizzly bear) CXCL14 – 100%
Ursus maritimus (polar bear) CXCL14 – 100%
Vulpes vulpes (red fox) CXCL14 – 100%
Zalophus californianus (California sea lion) CXCL14 – 100%
More… https://blast.ncbi.nlm.nih.gov