Human TNF-R1 Recombinant Protein

Catalog Number:: RP1807H
Application:: Cell Culture, Control, ELISA, ELISpot Control, Western Blot Control
100% Homology:: Gorilla gorilla gorilla (western lowland gorilla), Homo sapiens (human), Pongo abelii (Sumatran orangutan)

Product Description

Human TNF-R1 (Tumor Necrosis Factor Receptor 1, CD120a) (catalog RP1807H) is a yeast-derived receptor protein supplied lyophilized without carrier protein in 10% trehalose; it has no affinity tags and is naturally endotoxin-free, and should be reconstituted in sterile PBS that contains at least 0.1% carrier protein. The protein is ~20.5 kDa, 182 amino acids long (full sequence provided), and >98% pure by SDS-PAGE, with 100% amino-acid homology to human, western lowland gorilla, and Sumatran orangutan. Store at -20°C (stable up to twelve months from date of receipt; working aliquots with carrier protein stable ~3 months) and avoid repeated freeze/thaw cycles. Product origin is the USA. It is commonly used to study TNF-R1 signaling and immune responses (including regulation of inflammation, apoptosis, and TNF-mediated signaling pathways); typical experimental uses include cell-culture stimulation and receptor-binding assays, cytokine signaling studies, ELISA and neutralization assays, flow-cytometry and Western blot controls, and antibody generation/validation. Kingfisher Biotech products are supplied for research applications and are not intended for medicinal, diagnostic, or therapeutic use.

Properties/Specifications

Amino Acid Sequence	LVPHLGDREK RDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCRK NQYRHYWSEN LFQCFNCSLC LNGTVHLSCQ EKQNTVCTCH AGFFLRENEC VSCSNCKKSL ECTKLCLPQI ENVKGTEDSG TT (182)
Endotoxin	Naturally endotoxin-free
Form	Lyophilized
Storage Conditions	-20°C
Molecular Weight	20.5 kDa
Purity	>98% as visualized by SDS-PAGE analysis.
Affinity Tag	None
aminoAcids	182
Carrier Protein	None
Expression System	Yeast
Form	Lyophilized
Country Of Origin	USA

Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane receptor that binds tumor necrosis factor-alpha (TNFα).