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Atlantic Salmon CCL28 (Yeast-derived Recombinant Protein) - 5 micrograms

RP1878AS-005
$150.00
In Stock
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Bulk quantities of proteins are available. Please contact us for bulk pricing.

CCL28, also known as mucosae-associated epithelial chemokine (MEC), CCK1 and SCYA28, is a member of the CC chemokine subfamily. CCL28 regulates the chemotaxis of cells expressing the chemokine receptors CCR3 and CCR10. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. It is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. CCL28 has also been implicated in the migration of IgA-expressing cells to the mammary gland, salivary gland, intestine and other mucosal tissues. It has also been shown as a potential antimicrobial agent effective against certain pathogens, such as Gram negative and Gram positive bacteria and the fungus Candida albicans.

Alternate Names - Chemokine (C-C motif) ligand 28, CCL28, mucosae-associated epithelial chemokine, MEC, CCK1, SCYA28

Homology Across Species
Salmo salar (Atlantic salmon) CCL28 – 100%
Salmo trutta (river trout) CCL28 – 97%
More - https://blast.ncbi.nlm.nih.gov/

Catalog No.:
RP1878AS-005
Quantity:
5 ug
Source:
The Atlantic Salmon CCL28 recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Atlantic Salmon CCL28 recombinant protein has a predicted molecular weight of 8.1 kDa.
Protein Sequence:

GIPKCCVTTS MNIPTNVLRK VERAEMQRSN GVCDINALVL HVKGKKLCTH PKVKRKLKRM QRKKDGKPKR N (71)

Country of Origin:
USA
Applications:
The Atlantic Salmon CCL28 (MEC, CCK1, SCYA28) endotoxin-free recombinant protein can be used in cell culture, as an CCL28 ELISA Standard, and as a Western Blot Control.
None at this time

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