Mouse CCL6 (C–C motif chemokine ligand 6, also known as C10) is a proinflammatory chemokine that plays an important role in immune cell recruitment and regulation of inflammatory responses in mice (Mus musculus). CCL6 belongs to the CC chemokine family, which includes chemokines such as CCL3, CCL4, CCL5, and CCL2 that regulate leukocyte trafficking during immune activation. In mice, CCL6 is produced primarily by macrophages, neutrophils, dendritic cells, and epithelial cells in response to infection, inflammatory stimuli, or tissue injury. CCL6 exerts its biological effects mainly through interaction with chemokine receptors such as CCR1, promoting chemotaxis and activation of monocytes/macrophages, neutrophils, and lymphocytes at sites of inflammation. In murine physiology, CCL6 contributes to host defense against bacterial and parasitic infections, as well as to regulation of inflammatory responses in tissues such as the lung, liver, and gastrointestinal tract. Because CCL6 is largely rodent-specific and does not have a direct human ortholog, it has been widely studied in mouse models of inflammation, infection, and immune-mediated disease, helping to elucidate chemokine-driven leukocyte recruitment and inflammatory signaling pathways in experimental immunology research.