Bulk quantities of Human IL-36RA protein are available.
Please contact us for pricing.
Molecular Weight (calculated) - 16.8kDa
Amino Acid Sequence - MVLSGALCFR MKDSALKVLY LHNNQLLAGG LHAGKVIKGE EISVVPNRWL DASLSPVILG VQGGSQCLSC GVGQEPTLTL EPVNIMELYL GAKESKSFTF YRRDMGLTSS FESAAYPGWF LCTVPEADQP VRLTQLPENG GWNAPITDFY FQQC (154)
Gene ID - 26525
Homology Across Species
Homo sapiens (human) IL-36RA – 100%
Gorilla gorilla gorilla (western lowland gorilla) IL-36RA – 99%
Pan troglodytes (chimpanzee) IL-36RA – 99%
Pan paniscus (pygmy chimpanzee) IL-36RA – 99%
Macaca nemestrina (pig-tailed macaque) IL-36RA – 98%
Macaca fascicularis (crab-eating macaque) IL-36RA – 98%
Theropithecus gelada (gelada) IL-36RA – 98%
Piliocolobus tephrosceles (Ugandan red Colobus) IL-36RA – 98%
Trachypithecus francoisi (Francois's langur) IL-36RA – 98%
Pongo abelii (Sumatran orangutan) IL-36RA – 98%
Nomascus leucogenys (northern white-cheeked gibbon) IL-36RA – 98%
Hylobates moloch (silvery gibbon) IL-36RA – 98%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
Alternate Names - IL36RN, FIL1, FIL1(DELTA), FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, IL-36Ra, PSORS14, interleukin 36 receptor antagonist
MVLSGALCFR MKDSALKVLY LHNNQLLAGG LHAGKVIKGE EISVVPNRWL DASLSPVILG VQGGSQCLSC GVGQEPTLTL EPVNIMELYL GAKESKSFTF YRRDMGLTSS FESAAYPGWF LCTVPEADQP VRLTQLPENG GWNAPITDFY FQQC (154)
Please note that Cookies and JavaScript are required for you to view this website.
Check if you have Cookies and JavaScript enabled in your browser