Bovine CCL14 (C-C motif chemokine ligand 14), also known as HCC-1 (Hemofiltrate CC chemokine-1), is a member of the CC chemokine family that participates in leukocyte trafficking and regulation of inflammatory responses in cattle (Bos taurus). CCL14 is produced primarily by monocytes, macrophages, epithelial cells, and certain stromal tissues, and—following proteolytic activation—functions through chemokine receptors such as CCR1, CCR3, and CCR5 to promote chemotaxis of monocytes, eosinophils, and specific T lymphocyte subsets. Similar to other species, bovine CCL14 is synthesized as a precursor molecule that requires processing to achieve full biological activity. In healthy cattle, basal expression is generally low but detectable, contributing to immune surveillance; however, expression may increase during mastitis, respiratory disease, enteric infection, parasitic challenge, or other inflammatory conditions. In veterinary and agricultural research, bovine CCL14 is of interest as a mediator of mononuclear and eosinophilic cell recruitment and as a biomarker of inflammatory activation and host–pathogen interactions in cattle.