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Ferret/Mink Leukemia Inhibitory Factor (LIF) (Yeast-derived Recombinant Protein) - 25 micrograms

RP2133FT-025
$300.00
In Stock
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Bulk quantities of Ferret/Mink LIF protein are available.
Please contact us for pricing.

Ferret/Mink LIF Specifications

Molecular Weight (calculated) - 19.7kDa

Amino Acid Sequence - TPLPITPVNA TCATRHPCHS NLMNQIRNQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKTRL VELYRIIAYL GASLGNITRD QKVLNPNALS LHSKLNATAD ILRGLLSNVL CRLCNKYHVA HVDVAYGPDT SGKDVFQKKK LGCQLLGKYK QVIAVVAQAF (180)

Gene ID - 101674557

Homology Across Species
Mustela putorius furo (domestic ferret) LIF – 100%
Neogale vison (American mink) LIF – 100%
Mustela erminea (ermine) LIF – 100%
This amino acid sequence has greater than or equal to 98% homology across various species, including, ferret, mink, ermine, otter, puma, walrus, cheetah, seal, lion, badger, and cat.
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

LIF Background

Leukemia inhibitory factor, or LIF, is a member of the IL-6 family. LIF affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. Leukemia inhibitory factor derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to LIF include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. p53 regulated LIF has been shown to facilitate implantation in the mouse model and possibly in humans. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. LIF is typically added to stem cell culture medium to reduce spontaneous differentiation.

Alternate Names - LIF, CDF, DIA, HILDA, MLPLI, leukemia inhibitory factor, interleukin 6 family cytokine, LIF interleukin 6 family cytokine

Catalog No.:
RP2133FT-025
Quantity:
25 ug
Source:
The Ferret/Mink LIF recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Ferret/Mink LIF recombinant protein has a predicted molecular weight of 19.7 kDa.
Protein Sequence:

TPLPITPVNA TCATRHPCHS NLMNQIRNQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKTRL VELYRIIAYL GASLGNITRD QKVLNPNALS LHSKLNATAD ILRGLLSNVL CRLCNKYHVA HVDVAYGPDT SGKDVFQKKK LGCQLLGKYK QVIAVVAQAF (180)

Alias:
LIF
Country of Origin:
USA
Applications:
The Ferret/Mink LIF endotoxin-free recombinant protein can be used in cell culture, as an LIF ELISA Standard, and as a Western Blot Control.
None at this time

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USA

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