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Human IL-11 (Yeast-derived Recombinant Protein) - 25 micrograms

RP2153H-025
$300.00
In Stock
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Bulk quantities of Human IL-11 protein are available.
Please contact us for pricing.

Human IL-11 Specifications

Molecular Weight (calculated) - 18.4kDa

Amino Acid Sequence - RVSPDPRAEL DSTVLLTRSL LADTRQLAAQ LRDKFPADGD HNLDSLPTLA MSAGALGALQ LPGVLTRLRA DLLSYLRHVQ WLRRAGGSSL KTLEPELGTL QARLDRLLRR LQLLMSRLAL PQPPPDPPAP PLAPPSSAWG GIRAAHAILG GLHLTLDWAV RGLLLLKTRL (170)

Gene ID - 3589

Homology Across Species
Homo sapiens (human) IL-11 – 100%
Gorilla gorilla gorilla (western lowland gorilla) IL-11 – 100%
Pan troglodytes (chimpanzee) IL-11 – 100%
Pan paniscus (pygmy chimpanzee) IL-11 – 100%
Pongo abelii (Sumatran orangutan) IL-11 – 100%
Pongo pygmaeus (Bornean orangutan) IL-11 – 100%
Nomascus leucogenys (northern white-cheeked gibbon) IL-11 – 100%
Hylobates moloch (silvery gibbon) IL-11 – 100%
This sequence has 98% or greater homology across various species of capuchins and monkeys.
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

IL-11 Background

Interleukin 11 (IL-11 or adipogenesis inhibitory factor) is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. Signal specificity is provided by the IL-11Rα subunit which is expressed at high levels in fibroblasts and other stromal cells but not immune cells, unlike IL-6 receptors that are expressed at highest levels in immune cells and lowly expressed in stromal cells. IL-11 has been shown to regulate adipogenesis, osteoclastogenesis, neurogenesis and platelet maturation. Over-expression of IL-11 is associated with a variety of cancers and may provide a link between inflammation and cancer.

Alternate Names - IL11, AGIF, IL-11, interleukin 11

Catalog No.:
RP2153H-025
Quantity:
25 ug
Source:
The Human IL-11 recombinant protein was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
The Human IL-11 recombinant protein has a predicted molecular weight of 18.4 kDa.
Protein Sequence:

RVSPDPRAEL DSTVLLTRSL LADTRQLAAQ LRDKFPADGD HNLDSLPTLA MSAGALGALQ LPGVLTRLRA DLLSYLRHVQ WLRRAGGSSL KTLEPELGTL QARLDRLLRR LQLLMSRLAL PQPPPDPPAP PLAPPSSAWG GIRAAHAILG GLHLTLDWAV RGLLLLKTRL (170)

Country of Origin:
USA
Applications:
The Human IL-11 endotoxin-free recombinant protein can be used in cell culture, as a ELISA Standard, and as a Western Blot Control.
None at this time

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USA

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