Rabbit CXCL9 (C-X-C motif chemokine ligand 9), also known as MIG (monokine induced by interferon-γ), is a proinflammatory chemokine belonging to the CXC chemokine family, which also includes CXCL10 (IP-10) and CXCL11 (I-TAC) that regulate T-cell recruitment during interferon-driven immune responses. In rabbits (Oryctolagus cuniculus), CXCL9 is produced by macrophages, dendritic cells, endothelial cells, and epithelial cells in response to interferon-γ (IFN-γ) and other inflammatory signals during infection or immune activation. CXCL9 signals primarily through the chemokine receptor CXCR3, expressed on activated T lymphocytes, natural killer (NK) cells, and other immune cells, promoting chemotaxis and recruitment of these cells to sites of infection or inflammation. In rabbit immunity, CXCL9 contributes to Th1-type cell-mediated immune responses against intracellular pathogens, particularly within the lung and lymphoid tissues. Rabbits are also widely used as animal models for tuberculosis and other granulomatous diseases, where CXCL9 participates in the interferon-regulated chemokine network that recruits T cells to infected tissues and supports granuloma formation, making rabbit CXCL9 important for studying T-cell trafficking, inflammatory signaling, and host immune responses to intracellular pathogens.