Feline CCL14 (C-C motif chemokine ligand 14), also known as HCC-1 (Hemofiltrate CC chemokine-1), is a member of the CC chemokine family involved in leukocyte trafficking and immune regulation in cats (Felis catus). CCL14 is produced primarily by monocytes, macrophages, epithelial cells, and certain stromal tissues, and is believed to function through chemokine receptors such as CCR1, CCR3, and CCR5 following proteolytic activation of its precursor form. Like its human counterpart, feline CCL14 is likely synthesized as a relatively less active precursor that requires processing to achieve full chemotactic activity. In healthy cats, basal expression is expected to be low to moderate, contributing to immune surveillance, but levels may increase during inflammatory stimulation, infection, tissue injury, or neoplastic disease. In veterinary and comparative medicine research, feline CCL14 is of interest as a mediator of monocyte and eosinophil recruitment and as a potential biomarker in chronic inflammatory conditions, allergic disease, and tumor-associated immune responses. Characterization of feline CCL14 provides insight into chemokine-driven leukocyte trafficking and immune regulation in feline health and translational immunology research.