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Equine IL-2 Biotinylated Recombinant Protein
- Catalog Number:
- RPB1789E
- Availability:
- In stock
- Application:
- Cell Culture
- 100% Homology:
- Equus asinus (ass), Equus caballus (horse), Equus przewalskii (Przewalski's horse), Equus quagga (Plains zebra)
- Label:
- Biotin
- The Equine IL-2 Biotinylated yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Equine IL-2 Biotinylated applications are for cell culture. Equine IL-2 Biotinylated yeast-derived recombinant protein can be purchased in multiple sizes. Equine IL-2 Biotinylated Specifications: (Molecular Weight: 14.9 kDa) (Amino Acid Sequence: APTSSSKRET QQQLKQLQMD LKLLLEGVNN NKNPKLSKML TFKINMPKKA TELKHLQCLE EELKPLEEML KNFLSKDIKE LMSNINVTVL GLKGSETRFT CEYDDETGTI VEFLNKWITF CQSIFSTMT) (Gene ID: 100034204). For research use only.
| Amino Acid Sequence | APTSSSKRET QQQLKQLQMD LKLLLEGVNN NKNPKLSKML TFKINMPKKA TELKHLQCLE EELKPLEEML KNFLSKDIKE LMSNINVTVL GLKGSETRFT CEYDDETGTI VEFLNKWITF CQSIFSTMT (129) |
| Endotoxin | Naturally endotoxin-free |
| Storage Conditions | -20°C |
| Purity | >98% as visualized by SDS-PAGE analysis. |
| Country Of Origin | USA |
- Equine IL-2 (Interleukin-2) is a central T cell-derived cytokine that regulates lymphocyte proliferation, differentiation, and immune homeostasis in horses (Equus caballus). IL-2 is produced primarily by activated CD4⁺ and CD8⁺ T lymphocytes following antigen recognition and costimulatory signaling, and it functions through the IL-2 receptor complex (IL-2Rα/CD25, IL-2Rβ, and the common γ chain) to promote clonal expansion of antigen-specific T cells, enhance cytotoxic T lymphocyte and natural killer (NK) cell activity, and support development and maintenance of regulatory T cells (Tregs). In healthy horses, basal IL-2 expression is generally low but increases during infection, vaccination, and immune stimulation. Altered IL-2 responses have been associated with equine herpesvirus (EHV) infection, equine influenza, strangles (Streptococcus equi), equine infectious anemia virus (EIAV), and immune-mediated inflammatory diseases. Horses serve as important natural models for viral respiratory disease, chronic inflammatory airway disease (equine asthma), and lentiviral infection (EIAV as a model for HIV). In veterinary and comparative medicine research, equine IL-2 is widely used as a biomarker of T cell activation and cell-mediated immunity and is studied to evaluate vaccine efficacy, host-pathogen interactions, and immune regulation in equine health.
10 ug
Price: $200.00