Swine IFN alpha 1 Biotinylated Recombinant Protein

The Swine IFN alpha 1 Biotinylated yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Swine IFN alpha 1 Biotinylated applications are for cell culture. Swine IFN alpha 1 Biotinylated yeast-derived recombinant protein can be purchased in multiple sizes. Swine IFN alpha 1 Biotinylated Specifications: (Molecular Weight: 19.0 kDa) (Amino Acid Sequence: CDLPQTHSLAHTRALRLLAQMRRISPFSCLDHRRDFGSPHEAFGGNQVQKAQAMALVHEMLQQTFQLFSTEGSAAAWNESLLHQFCTGLDQQLRDLEACVMQGAGLEGTPLLEEDSILAVRKYFHRLTLYLQEKSYSPCAWEIVRAEVMRSFSSSRNLQDRLRKKE (166)) (Gene ID: 397686). For research use only.

Amino Acid Sequence	CDLPQTHSLA HTRALRLLAQ MRRISPFSCL DHRRDFGSPH EAFGGNQVQK AQAMALVHEM LQQTFQLFST EGSAAAWNES LLHQFCTGLD QQLRDLEACV MQGAGLEGTP LLEEDSILAV RKYFHRLTLY LQEKSYSPCA WEIVRAEVMR SFSSSRNLQD RLRKKE (166)
Endotoxin	Naturally endotoxin-free

Storage Conditions	-20°C
Purity	>98% as visualized by SDS-PAGE analysis.
Country Of Origin	USA

Swine Interferon-Alpha (IFN-α) is a type I interferon produced primarily by plasmacytoid dendritic cells and virus-infected cells in pigs (Sus scrofa domesticus), where it plays a central role in early innate antiviral defense. Upon binding to the type I interferon receptor complex (IFNAR1/IFNAR2), swine IFN-α activates JAK/STAT signaling pathways, leading to induction of interferon-stimulated genes (ISGs) that inhibit viral replication, enhance antigen presentation, and promote activation of natural killer (NK) cells and adaptive immune responses. IFN-α is critically involved in host responses to economically significant viral infections such as porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus, African swine fever virus (ASFV), porcine epidemic diarrhea virus (PEDV), and classical swine fever virus (CSFV), where viral immune evasion strategies often target type I interferon pathways to enhance replication and persistence. The magnitude and timing of IFN-α responses can influence disease severity, viral shedding, and vaccine efficacy. In translational research, pigs serve as valuable large-animal models due to physiological and immunological similarities to humans, and characterization of swine IFN-α supports studies of respiratory viral pathogenesis, antiviral therapeutics, vaccine development, and comparative type I interferon biology relevant to both veterinary medicine and human infectious disease research.

Choose a size

Price: $200.00