Bulk quantities of Ferret IL-1RA antibody are available.
Please contact us for pricing.
Ferret IL-1RA ELISA Data
Reactivity - ELISA
Recombinant ferret IL-1RA - Strong
Recombinant bovine IL-1RA - Weak
Recombinant canine IL-1RA - Strong
Recombinant chicken IL-1RA - None
Recombinant dolphin IL-1RA - Weak
Recombinant equine IL-1RA - Weak
Recombinant mouse IL-1RA - None
Recombinant rabbit IL-1RA - None
Recombinant swine IL-1RA - None
Quantity - 100 ug
Antibody Type - Polyclonal
Host - Rabbit
Immunogen - Recombinant Ferret IL-1RA
Purification - Antigen-affinity
Label - None
The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress. The biological properties of IL-37 (IL-1F7) are mainly those of down-regulating inflammation.
Alternate Names - IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4, interleukin 1 receptor antagonist
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