Bulk quantities of proteins are available. Please contact us for bulk pricing.
IL-22 is a member of the IL-10 family, which includes IL-19, IL-20, IL-24, and IL-26. This family represents a class of potent mediators of cellular inflammatory responses. IL-22 shares use of IL-10R2 in cell signaling with other members of this family. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by a subset of splenic cells and can also be produced by Th17 cells. IL-22 likely plays a role in the coordinated response of both adaptive and innate immune systems.
Alternate Names - IL22, IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, interleukin 22
IL-22 Homology Across Species
Macaca mulatta (Rhesus monkey) IL-22 – 100%
Macaca nemestrina (pig-tailed macaque) IL-22 – 100%
Chlorocebus sabaeus (green monkey) IL-22 – 99%
Mandrillus leucophaeus (drill) IL-22 – 99%
Papio anubis (olive baboon) IL-22 – 99%
Pongo abelii (Sumatran orangutan) IL-22 – 97%
Rhinopithecus bieti (black snub-nosed monkey) IL-22 – 97%
Aotus nancymaae (Ma's night monkey) IL-22 – 96%
Callithrix jacchus (white-tufted-ear marmoset) IL-22 – 96%
Homo sapiens (human) IL-22 – 96%
Rhinopithecus roxellana (golden snub-nosed monkey) IL-22 – 96%
Pan paniscus (pygmy chimpanzee) IL-22 – 95%
Pan troglodytes (chimpanzee) IL-22 – 95%
Please note that Cookies and JavaScript are required for you to view this website.
Check if you have Cookies and JavaScript enabled in your browser