Bulk quantities of Ferret APRIL protein are available.
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Molecular Weight (calculated) - 16.6kDa
Amino Acid Sequence - AALMHKHKQK KKHSVLHLVP INITSKEDSD VTEVMWQPAL KRGRGLEAQG YVVRVWDAGV YLLYSQVLFH DVTFTMGQVV SREGQGRQET LFRCVRSMPS NPDWAYNSCY SAGVFHLHQG DALSVTIPRG RAKLSLSPHG TFLGLVKL (148)
Gene ID - 101683970 (Ferret) 116578386 (Ermine)
Homology Across Species
Mustela putorius furo (domestic ferret) APRIL- 100%
Mustela erminea (ermine) APRIL – 100%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Cell Culture, ELISA Standard, Western Blot Control
Tumor necrosis factor ligand superfamily member 13 (TNFSF13) also known as a proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor ligand (TNF) ligand family. Nineteen cytokines have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18). APRIL/TNFSF13 is expressed by macrophages and dendritic cells. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development.
Alternate Names - TNFSF13, APRIL, CD256, TALL-2, TALL2, TRDL-1, ZTNF2, UNQ383/PRO715, TNLG7B, tumor necrosis factor superfamily member 13, TNF superfamily member 13
AALMHKHKQK KKHSVLHLVP INITSKEDSD VTEVMWQPAL KRGRGLEAQG YVVRVWDAGV YLLYSQVLFH DVTFTMGQVV SREGQGRQET LFRCVRSMPS NPDWAYNSCY SAGVFHLHQG DALSVTIPRG RAKLSLSPHG TFLGLVKL (148)
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