Egyptian Rousette Bat IL-17A ELISpot

Catalog Number:
SPOT2326BT
Availability:
In stock
Application:
ELISpot
100% Homology:
Rousettus aegyptiacus (Egyptian rousette)

Components

UsageQuantityComponent
Capture Antibody100 µgKP2269BT-100
Detection Antibody50 µg X 2KPB2270BT-050
Standard Control5 µgRP2121BT-005
  • Egyptian Rousette Bat IL-17A ELISpot contains Capture Antibody, Standard Control, and Detection Antibody for development of up to two (2) ELISpot assays. Other required materials and reagents are not supplied. The antibodies have been determined to function in an ELISpot with the Standard Control provided. Components may also be purchased separately. For research use only.
Storage Conditions2°C to 8°C
Country Of OriginUSA
Egyptian rousette bat IL-17A (Interleukin-17A) is a pro-inflammatory cytokine belonging to the IL-17 family that plays a key role in regulating host defense and inflammatory responses in the Egyptian rousette bat (Rousettus aegyptiacus). IL-17A is produced primarily by Th17 cells and other IL-17–producing lymphocytes, including γδ T cells and innate lymphoid cells, in response to infection or immune stimulation. It acts on epithelial, endothelial, and stromal cells to induce expression of pro-inflammatory cytokines, chemokines, and antimicrobial peptides, thereby promoting neutrophil recruitment and enhancing mucosal immunity. In healthy bats, basal IL-17A expression is expected to be low, but levels may increase during bacterial or fungal infection, tissue injury, or experimental immune activation. Given that Egyptian rousette bats are natural reservoir hosts for pathogens such as Marburg virus and other zoonotic viruses, characterization of IL-17A responses in this species is of particular interest for understanding how bats balance effective pathogen control with limited immunopathology. Study of Egyptian rousette bat IL-17A provides valuable insight into Th17-mediated immunity, mucosal defense mechanisms, and the unique immune regulatory strategies that enable bats to tolerate viral infections.
Price: $1,200.00

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